Antimitotic Activity of Gossypol and Gossypolone
نویسندگان
چکیده
منابع مشابه
antioxidant and antimicrobial activity of allium jesdianum extract
چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...
Effect of Gossypol, Apogossypol and Gossypolone on Fatty Acids Pattern of Lipid Fractions in Rat Serum and Seminal Fluid
The fatty acids pattern of the total lipid fractions of male rat serum and seminal fluids were studied under the effect of gossypol and some of its metabolites (Apogossypol and gossypolone). The applied dose of gossypol and its derivatives exhibits some metabolic effects such as significant decrease of the saturated fatty acids and a significant increase of polyunsaturated fatty acids. In the s...
متن کاملThe Effect of Gossypol, Gossypolone and Apogossypol on the Lipids of Male Rat Serum and Seminal Fluid
The neutral and polar lipids of serum and seminal fluid of male rats were investigated under .t~e effect of gossypol acetic acid, apogossypol and gossypolone. The. total phospholipids. and. the neutral serum l.Ipids showed positive and negative significant correlation with the duratiOn .of gossypol acetic acid treatment, :espe~tively. At. the same time, free fatty acids content significantly in...
متن کاملAntimitotic and antitubulin activity of the tumor inhibitor steganacin.
Steganacin, a newly isolated tumor inhibitor, completely inhibits cleavage in sea urchin eggs at 3 X 10(-7) M by preventing the formation of the mitotic apparatus. Steganacin inhibits the polymerization of tubulin in vitro and also causes a slow depolymerization of preformed microtubules. Optical ultracentrifuge studies of steganacin-treated tubulin show a small reduction in 20 S and 30 S peaks...
متن کاملdetection of volatile compounds of medicinal plants with some nano-sorbents using modified or new methodologies and investigation of antioxidant activity of their methanolic extracts
in this work, a novel and fast method for direct analysis of volatile compounds (davc) of medicinal plants has been developed by holding a filament from different parts of a plant in the gc injection port. the extraction and analysis of volatile components of a small amount of plant were carried out in one-step without any sample preparation. after optimization of temperature, extraction time a...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2001
ISSN: 1388-0209,1744-5116
DOI: 10.1076/phbi.39.2.120.6257